Distinct Regions of Right Temporo-Parietal Junction Are Selective for Theory of Mind and Exogenous Attention

TitleDistinct Regions of Right Temporo-Parietal Junction Are Selective for Theory of Mind and Exogenous Attention
Publication TypeJournal Article
Year of Publication2009
AuthorsScholz, J., Triantafyllou C., Whitfield-Gabrieli S., Brown E. N., & Saxe R.
Secondary AuthorsLauwereyns, J.
JournalPLoS ONE
Volume4
Issue3
Paginatione4869
Date Published03/2009
Abstract

In functional magnetic resonance imaging (fMRI) studies, a cortical region in the right temporo-parietal junction (RTPJ) is recruited when participants read stories about people’s thoughts (‘Theory of Mind’). Both fMRI and lesion studies suggest that a region near the RTPJ is associated with attentional reorienting in response to an unexpected stimulus. Do Theory of Mind and attentional reorienting recruit a single population of neurons, or are there two neighboring but distinct neural populations in the RTPJ? One recent study compared these activations, and found evidence consistent with a single common region. However, the apparent overlap may have been due to the low resolution of the previous technique. We tested this hypothesis using a high-resolution protocol, within-subjects analyses, and more powerful statistical methods. Strict conjunction analyses revealed that the area of overlap was small and on the periphery of each activation. In addition, a bootstrap analysis identified a reliable 6–10 mm spatial displacement between the peak activations of the two tasks; the same magnitude and direction of displacement was observed in within-subjects comparisons. In all, these results suggest that there are neighboring but distinct regions within the RTPJ implicated in Theory of Mind and orienting attention.

URLhttp://dx.plos.org/10.1371/journal.pone.0004869
DOI10.1371/journal.pone.000486910.1371
Short TitlePLoS ONE

Download: