Using individual functional channels of interest to study cortical development with fNIRS

TitleUsing individual functional channels of interest to study cortical development with fNIRS
Publication TypeJournal Article
Year of Publication2017
AuthorsPowell, L. J., Deen B., & Saxe R.
JournalDevelopmental Science
Issue4
Paginatione12595
Date Published07/2017
Abstract

Functional near-infrared spectroscopy (fNIRS) is a noninvasive neuroimaging technique that could be uniquely effective for investigating cortical function in human infants. However, prior efforts have been hampered by the difficulty of aligning arrays of fNIRS optodes placed on the scalp to anatomical or functional regions of underlying cortex. This challenge can be addressed by identifying channels of interest in individual participants, and then testing the reliability of those channels’ response profiles in independent data. Using this approach, cortical regions with preferential responses to faces versus scenes, and to scenes versus faces, were observed reliably in both adults and infants. By contrast, standard analysis techniques did not reliably identify significant responses to both categories in either age group. These results reveal sceneresponsive regions, and confirm face-responsive regions, in preverbal infants. More generally, the analysis approach will be a robust and sensitive tool for future characterization of the early functional development of the human brain.

URLhttps://onlinelibrary.wiley.com/doi/full/10.1111/desc.12595
DOI10.1111/desc.12595
Short TitleDev Sci

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