|Title||Similar Brain Activation during False Belief Tasks in a Large Sample of Adults with and without Autism|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Dufour, N., Redcay E., Young L., Mavros P. L., Moran J. M., Triantafyllou C., Gabrieli J. D. E., & Saxe R.|
|Secondary Authors||Gilbert, S.|
Reading about another person’s beliefs engages ‘Theory of Mind’ processes and elicits highly reliable brain activation across individuals and experimental paradigms. Using functional magnetic resonance imaging, we examined activation during a story task designed to elicit Theory of Mind processing in a very large sample of neurotypical (N = 462) individuals, and a group of high-functioning individuals with autism spectrum disorders (N = 31), using both region-of-interest and wholebrain analyses. This large sample allowed us to investigate group differences in brain activation to Theory of Mind tasks with unusually high sensitivity. There were no differences between neurotypical participants and those diagnosed with autism spectrum disorder. These results imply that the social cognitive impairments typical of autism spectrum disorder can occur without measurable changes in the size, location or response magnitude of activity during explicit Theory of Mind tasks administered to adults.
|Short Title||PLoS ONE|